Salivary egf concentration in adults with reflux chronic laryngitis before and after treatment: preliminary results.

Comparative study of salivary pH and volume in adults with chronic laryngopharyngitis by gastroesophageal reflux disease before and after treatment Summary

Chronic Laryngitis and Gastroesophageal Reflux Disease

78 INTRODUCTION Gastroesophageal reflux disease (GERD) is implicated in many patients with chronic laryngitis. Ear, nose and throat (ENT) physicians often refer to this condition as laryngopharyngeal reflux (LPR) representing the retrograde movement of gastric contents, including acid, pepsin as well as bile acids, into the laryngopharynx (1,2). Typical LPR symptoms include dysphonia, globus ph...

MRSA chronic bacterial laryngitis: A growing problem.

OBJECTIVES Chronic bacterial infection of the larynx is characterized by long-standing hoarseness and exudative laryngitis. Prolonged antibiotic therapy is required to clear the infection, and methicillin-resistant staphylococcus aureus (MRSA) may be the responsible pathogen. The objective of this study was to describe the presentation, comorbidities, treatment response, and underlying etiology...

Salivary transforming growth factor alpha in patients with Sjögren's syndrome and reflux laryngitis.

INTRODUCTION Saliva plays a key role in the homeostasis of the digestive tract, through its inorganic components and its protein growth factors. Sjögren's syndrome patients have a higher prevalence of gastroesophageal reflux disease and laryngopharyngeal reflux. Decreased salivary transforming growth factor alpha levels were observed in dyspeptic patients, but there have been no studies in pati...

The human laryngeal microbiome: effects of cigarette smoke and reflux

Prolonged diffuse laryngeal inflammation from smoking and/or reflux is commonly diagnosed as chronic laryngitis and treated empirically with expensive drugs that have not proven effective. Shifts in microbiota have been associated with many inflammatory diseases, though little is known about how resident microbes may contribute to chronic laryngitis. We sought to characterize the core microbiot...